Open AccessToday’s choice of antiepileptic therapy: stages and recommendations
Author(s) -
К. В. Воронкова,
А. В. Никитин,
И. Г. Рудакова,
П. Н. Власов,
С. Г. Бурд,
А. В. Лебедева,
G. N. Avakyan
Publication year - 2018
Publication title -
èpilepsiâ i paroksizmalʹnye sostoâniâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 1
eISSN - 2311-4088
pISSN - 2077-8333
DOI - 10.17749/2077-8333.2018.10.2.074-081
Subject(s) - antiepileptic drug , epilepsy , intensive care medicine , medicine , key (lock) , risk analysis (engineering) , drug , clinical trial , computer science , psychiatry , computer security , pathology
At present, treatment recommendations are developed considering the principles of evidence-based medicine. General practitioners (GP) are offered a choice of different medications with the known characteristics of efficacy and tolerance. For a GP, the right choice of the optimal drug from the proposed list may become a problem. Therefore, it is important not only to provide complete information on all treatment options for a patient with epilepsy, but also discuss a scheme of the proposed therapy (“key”) so to guide a GP through the treatment options and assess the possibility of alternative treatment strategies. Contrary to the trial and error method, when the drug efficacy and safety is assessed during the treatment, the proposed optimized approach allows for achieving a maximal therapeutic effect in patients with epilepsy.