Open AccessModern achievements in pharmacotherapy of osteoarthritis based on endo- and phenotyping
Author(s) -
И. В. Сарвилина,
О. А. Shavlovskaya,
О. А. Gromova,
А. В. Наумов,
М. Н. Шаров,
Yu. S. Prokofyeva
Publication year - 2021
Publication title -
farmakoèkonomika
Language(s) - English
Resource type - Journals
eISSN - 2070-4933
pISSN - 2070-4909
DOI - 10.17749/2070-4909/farmakoekonomika.2021.105
Subject(s) - osteoarthritis , pharmacotherapy , disease , medicine , epidemiology , clinical trial , musculoskeletal disease , intensive care medicine , alternative medicine , pathology
The review of medical literature is devoted to modern data in the field of diagnosis and treatment of osteoarthritis using endo- and phenotyping. It includes the latest data on the epidemiology of osteoarthritis of different localizations, modern definitions and classifications of osteoarthritis endotypes and phenotypes, pathobiochemical patterns and pathomorphological parallels of disease phenotypes, new methodological approaches to the phenotyping of osteoarthritis (prognostic, prescriptive phenotyping, alternative methods), as well as modern advances in pharmacotherapy of the disease based on data from selected randomized controlled trials and meta-analyzes.