Correction of melanin proteolytic activity upon modeling of alkali burns of the esophagus | Zendy

N. M. Chornenka | Zendy; K. Valetska | Zendy; Ya. Rayetska | Zendy; Л. І. Остапченко | Zendy

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Correction of melanin proteolytic activity upon modeling of alkali burns of the esophagus

Author(s) -

N. M. Chornenka,

K. Valetska,

Ya. Rayetska,

Л. І. Остапченко

Publication year - 2017

Publication title -

bulletin of taras shevchenko national university of kyiv series problems of physiological functions regulation

Language(s) - English

Resource type - Journals

eISSN - 2616-6410

pISSN - 1728-2624

DOI - 10.17721/2616_6410.2017.22.53-57

Subject(s) - proteolysis , normalization (sociology) , serine , proteolytic enzymes , esophagus , matrix metalloproteinase , chemistry , peptide hydrolases , biochemistry , pathological , medicine , pathology , enzyme , sociology , anthropology , protease

During the esophageal burns first and second degree, were observed the increase of total proteolytic activity and of the main proteinase (metalloproteinases and serine). Experimental melanin correction at a dose of 0.1 mg / kg contributed to the normalization of the pathological increase of total proteolytic activity and the activity of the main proteinase (metalloproteinases and serine), which indicates the normalization of the proteolysis system.

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