Glutathione system in the blood serum of rats in the dynamics of full-thickness wounds and with the influence of new pharmacological composition containing melanine | Zendy

O. Taburets | Zendy; K. Dvorshenko | Zendy; M. Tymoshenko | Zendy; V.V. Vereschaka | Zendy; Tetyana Beregova | Zendy; Л. І. Остапченко | Zendy

Open Access

Glutathione system in the blood serum of rats in the dynamics of full-thickness wounds and with the influence of new pharmacological composition containing melanine

Author(s) -

O. Taburets,

K. Dvorshenko,

M. Tymoshenko,

V.V. Vereschaka,

Tetyana Beregova,

Л. І. Остапченко

Publication year - 2017

Publication title -

bulletin of taras shevchenko national university of kyiv series problems of physiological functions regulation

Language(s) - English

Resource type - Journals

eISSN - 2616-6410

pISSN - 1728-2624

DOI - 10.17721/2616_6410.2017.22.5-8

Subject(s) - glutathione , glutathione reductase , glutathione peroxidase , antioxidant , chemistry , enzyme , pharmacology , biochemistry , medicine

The activity of enzymes of the glutathione link of the antioxidant system in rats with experimental full-thickness wound has been studied. It is established that in the serum of rats under the experimental model of the cut wound the level of recovered glutathione and glutathione reductase activity decreased, glutathione peroxidase and glutathione transferase activity increased. All investigated parameters normalized in dynamics after treatment with melanin.

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