Open AccessGlutathione system in the blood serum of rats in the dynamics of full-thickness wounds and with the influence of new pharmacological composition containing melanine
Author(s) -
O. Taburets,
K. Dvorshenko,
M. Tymoshenko,
V.V. Vereschaka,
Tetyana Beregova,
L. Ostapchenko
Publication year - 2017
Publication title -
vìsnik. problemi regulâcìï fìzìologìčnih funkcìj/vìsnik kiïvsʹkogo nacìonalʹnogo unìversitetu ìmenì tarasa ševčenka. serìâ: problemi regulâcìï fìzìologìčnih funkcìj
Language(s) - English
Resource type - Journals
eISSN - 2616-6410
pISSN - 1728-2624
DOI - 10.17721/2616_6410.2017.22.5-8
Subject(s) - glutathione , glutathione reductase , glutathione peroxidase , antioxidant , chemistry , enzyme , pharmacology , biochemistry , medicine
The activity of enzymes of the glutathione link of the antioxidant system in rats with experimental full-thickness wound has been studied. It is established that in the serum of rats under the experimental model of the cut wound the level of recovered glutathione and glutathione reductase activity decreased, glutathione peroxidase and glutathione transferase activity increased. All investigated parameters normalized in dynamics after treatment with melanin.