Open AccessExpression of AQP8 gene in rat duodenum with diarrhea upon long-term gastric hypochlorhydria
Author(s) -
A. S. Dranitsina,
K. Dvorshchenko,
D. M. Grebinyk,
L. Ostapchenko
Publication year - 2017
Publication title -
vìsnik. problemi regulâcìï fìzìologìčnih funkcìj/vìsnik kiïvsʹkogo nacìonalʹnogo unìversitetu ìmenì tarasa ševčenka. serìâ: problemi regulâcìï fìzìologìčnih funkcìj
Language(s) - English
Resource type - Journals
eISSN - 2616-6410
pISSN - 1728-2624
DOI - 10.17721/2616_6410.2017.22.20-25
Subject(s) - duodenum , crypt , diarrhea , stomach , medicine , gene , gene expression , biology , gastroenterology , biochemistry
The decreasing of Aqp8 gene's expression in rat duodenal villus and crypt epithelial cells against the background of intensification of free radical formation with diarrhea upon gastric hypoacidic conditions were shown. The level of above mentioned gene's expression both in villus and crypt epitheliocytes approached to the control value upon the treatment of hypoacidic rats with multiprobiotic Symbiter.