Open AccessKisspeptin-mediated regulation of the morpho-functional state of the rat testicles under the effect of silver nanoparticles
Author(s) -
V. Kalinovskyi,
A. S. Pustovalov,
M. Dzerzhynskyi,
G. Ya. Grodzyuk,
N. Andriushina
Publication year - 2016
Publication title -
vìsnik. problemi regulâcìï fìzìologìčnih funkcìj/vìsnik kiïvsʹkogo nacìonalʹnogo unìversitetu ìmenì tarasa ševčenka. serìâ: problemi regulâcìï fìzìologìčnih funkcìj
Language(s) - English
Resource type - Journals
eISSN - 2616-6410
pISSN - 1728-2624
DOI - 10.17721/2616_6410.2016.20.8-11
Subject(s) - silver nanoparticle , kisspeptin , downregulation and upregulation , nanoparticle , function (biology) , morpho , medicine , endocrinology , chemistry , microbiology and biotechnology , biology , hypothalamus , nanotechnology , materials science , biochemistry , gene
It was shown that silver nanoparticles downregulate reproductive system of male rats. At the same time, activation of the hypothalamic sex-function regulatory center did not result in any stimulatory effect on testes. We suppose that toxicity of silver nanoparticles is due to their direct action on the testicles.