Open AccessTesticular morpho-functional state of immature rats under the effect of gold nanoparticles and ions
Author(s) -
V. Kalinovskyi,
A. S. Pustovalov,
M. Dzerzhynskyi,
G. Ya. Grodzyuk,
N. Andriushina
Publication year - 2016
Publication title -
vìsnik - kiïvsʹkij nacìonalʹnij unìversitet ìmenì tarasa ševčenka. bìologìâ
Language(s) - English
Resource type - Journals
ISSN - 1728-2748
DOI - 10.17721/1728_2748.2016.71.23-26
Subject(s) - colloidal gold , endocrine system , medicine , endocrinology , chemistry , nanoparticle , ion , biophysics , microbiology and biotechnology , biology , materials science , nanotechnology , hormone , organic chemistry
Effect of ionic and colloidal gold on the testicular function of immature rats was investigated. It was shown that gold ions promote proliferative processes in the spermatogenic epithelium, and also increase interstitial cells' functional activity. At the same time, gold nanoparticles downregulated testicular endocrine function and slowed down puberty. To sum up, despite of the stimulatory nature of gold, transforming to nanoscale is accompanied by the obtaining of toxic properties.