Open AccessSafety of carotene-producing strains Bacillus sp. 1.1 and B. amyloliquefaciens UCM B-5113 for homoiothermal animals
Author(s) -
Oleksiy V. Nechypurenko,
M. Kharkota,
Л.В. Авдеева
Publication year - 2014
Publication title -
vìsnik - kiïvsʹkij nacìonalʹnij unìversitet ìmenì tarasa ševčenka. bìologìâ
Language(s) - English
Resource type - Journals
ISSN - 1728-2748
DOI - 10.17721/1728_2748.2014.68.21-24
Subject(s) - bacillus amyloliquefaciens , putrescine , bacillus (shape) , cadaverine , microbiology and biotechnology , biology , bacilli , group b , bacteria , food science , biochemistry , medicine , fermentation , enzyme , genetics
It was detected that the strains of carotenoid-producing Bacillus sp. 1.1 and B. amyloliquefaciens UCM B-5113 are safe for warm-blooded animals, also avirulent and do not show toxic and toxigenic effect. It was determined the absence of the ability of strains of Bacillus sp. 1.1 and B. amyloliquefaciens UCM B-5113 to produce putrescine and cadaverine. In experiments on mice was shown that oral and intraperitoneal administration of suspensions of the strains of bacilli, containing 15 billion cells/mouse did not cause the death of experimental animals and did not lead to pathologic changes in the tissues of their bodies. Thus, strains Bacillus sp. 1.1 and B. amyloliquefaciens UCM B-5113 are non-pathogenic and safe for warm-blooded animals.