Open AccessSchizophrenia following new-onset refractory status epilepticus secondary to antiphospholipid syndrome
Author(s) -
Mashael AlKhateeb,
Fatima Adem,
Amani Moqbel,
Salah Baz
Publication year - 2019
Publication title -
neurosciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.235
H-Index - 21
eISSN - 1658-3183
pISSN - 1319-6138
DOI - 10.17712/nsj.2018.3.20180014
Subject(s) - status epilepticus , refractory (planetary science) , schizophrenia (object oriented programming) , antiphospholipid syndrome , medicine , pediatrics , psychiatry , psychosis , epilepsy , thrombosis , physics , astrobiology
New-onset refractory status epilepticus (NORSE) is a drug-resistant status epilepticus that often has a catastrophic outcome. Our patient was diagnosed with NORSE and had an EEG reading that showed status epilepticus persisting for 8 months in general anesthesia. After autoimmune workup showed positive antiphospholipid antibodies, his seizure was controlled, and he was discharged with good condition apart from moderate cognitive impairment. However, he later developed schizophrenia. Although psychiatric disorders have been associated with antiphospholipid syndrome, to the best of our knowledge, it has not been reported to be associated with status epilepticus. We recommend vigilance of psychological complications of refractory status epilepticus patients for early psychiatric referral, diagnosis, and treatment.