Open AccessEffective application of integrative approach in treatment of neuroendocrine colon cancer. Clinical case
Author(s) -
М. М. Давыдов,
P. A. Zeynalovа,
А. А. Феденко,
E. K. Ibragimov,
D. A. Chekiny,
A. A. Filimonov,
E. V. Dementievа
Publication year - 2022
Publication title -
md-onco
Language(s) - English
Resource type - Journals
eISSN - 2782-6171
pISSN - 2782-3202
DOI - 10.17650/2782-3202-2022-2-1-28-32
Subject(s) - medicine , neuroendocrine tumors , colorectal cancer , microsatellite instability , gastrointestinal tract , colectomy , disease , oncology , palliative treatment , cancer , gastroenterology , biology , allele , biochemistry , microsatellite , gene
Neuroendocrine tumors are rare type of tumors of the gastrointestinal tract. Mostly the patient is diagnosed rather late, the tumors don’t have specific symptoms and there are no sensitive and specific methods of early diagnostics of the disease. Also, to date, the choice of antitumor treatment methods is limited. The article presents a clinical case of effective treatment of a neuroendocrine tumor of the colon with high level of microsatellite instability. After palliative partial colectomy, atypical resection of the liver, female patient with metastatic cancer of the descending colon has been receiving therapy with checkpoint inhibitors (PD-1) which led to long-term stabilization of the process.