Open AccessOverview of anticonvulsant therapy in full-term and premature neonates
Author(s) -
M.A. Ivzhits,
С. К. Зырянов,
Г. В. Родоман,
Irina Bondareva,
С.В. Думова,
О А Бабак,
Mikhail S. Chenkurov,
Г. А. Пуцман
Publication year - 2020
Publication title -
russkij žurnal detskoj nevrologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.139
H-Index - 2
eISSN - 2412-9178
pISSN - 2073-8803
DOI - 10.17650/2073-8803-2020-15-2-42-54
Subject(s) - anticonvulsant , pharmacokinetics , medicine , dosing , anticonvulsant drugs , full term , intensive care medicine , pediatrics , epilepsy , pharmacology , pregnancy , psychiatry , biology , genetics
Convulsions in full-term and especially in premature newborns are observable pathologies. Selection of anticonvulsant therapy is very difficult: newborns have particular pharmacokinetics of drugs, insufficient data on doses and therapeutic concentrations of anticonvulsants in the blood (premature infants mainly). This article is an overview, with an emphasis on the features of dosing and pharmacokinetics of anticonvulsants in term and preterm infants.