Open AccessClinical significance of changes in the expression level of markers of surrogate breast cancer subtypes in recurrent and metastatic foci (literature review)
Author(s) -
Ю. С. Круминь,
В. А. Хайленко,
Н. А. Козлов,
Г. Ю. Черемис,
А. В. Петровский,
Д. В. Хайленко,
Е. В. Артамонова,
Е. И. Коваленко
Publication year - 2021
Publication title -
opuholi ženskoj reproduktivnoj sistemy
Language(s) - English
Resource type - Journals
eISSN - 1999-8627
pISSN - 1994-4098
DOI - 10.17650/1994-4098-2020-16-3-41-45
Subject(s) - breast cancer , immunohistochemistry , metastatic breast cancer , estrogen receptor , oncology , medicine , estrogen , surrogate endpoint , protein expression , disease , cancer , clinical significance , pathology , biology , gene , biochemistry
The article analyzes data from the world literature for the period from 2005 to 2020 on the relationship between the variability of immunohistochemical expression of estrogen and progesterone receptors, HER2/neu protein and the index of proliferative activity in invasive breast cancer with the course of the disease and the response to medication.