Open AccessFlow cytometry in the diagnosis of plasma cell tumors and assessment of minimal residual disease
Author(s) -
Л. Ю. Гривцова,
T.Yu. Mushkarina,
В. В. Лунин,
P. A. Zeynalovа
Publication year - 2021
Publication title -
onkogematologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.118
H-Index - 3
eISSN - 2413-4023
pISSN - 1818-8346
DOI - 10.17650/1818-8346-2021-16-3-16-25
Subject(s) - minimal residual disease , flow cytometry , plasma cell myeloma , multiple myeloma , plasma cell , disease , pathology , plasma cell neoplasm , residual , hematopoietic cell , medicine , haematopoiesis , computer science , immunology , biology , stem cell , bone marrow , plasmacytoma , microbiology and biotechnology , algorithm
The article considers the features and possibilities of flow cytometric diagnostics of plasma cell neoplasms, taking into account the classification of lymphoid and hematopoietic tissue tumors of the World Health Organization, revision of 2017 and the NCCN clinical recommendations, 2021. Standardized flow cytometric protocols (the Euro-Flow conception) and algorithms for both the diagnosis of plasma cell tumors and the detection of minimal residual disease in plasma cell myeloma are described.