Open AccessRHD and RHCE genes polymorphism: literature review
Author(s) -
Л. Л. Головкина,
Р. С. Каландаров
Publication year - 2020
Publication title -
onkogematologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.118
H-Index - 3
eISSN - 2413-4023
pISSN - 1818-8346
DOI - 10.17650/1818-8346-2020-15-4-38-51
Subject(s) - genetics , gene , biology , serology , antigen , polymorphism (computer science) , rh blood group system , allele , antibody
The article provides a literature review about RHD and RHCE polymorphisms which encode different RhD and RhC antigen variants. The data about genes RHD and RHCE polymorphisms, RhD weak types, RhD partial types and RhC variants in Russians is presented for the first time. The molecular and serological characteristics of rare RhD and RhC antigens are summarized. The role of serological and molecular methods in Rhesus system antigens identifying is shown.