Open AccessThe experience of free light chains of immunoglobulin elimination in patients with monoclonal gammopathies
Author(s) -
Е. Г. Громова,
P. A. Zeynalovа,
Н. В. Любимова,
Ю. С. Тимофеев,
Н. Е. Кушлинский,
А. А. Семенова,
В. В. Лунин,
Ю. И. Ключагина
Publication year - 2019
Publication title -
onkogematologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.118
H-Index - 3
eISSN - 2413-4023
pISSN - 1818-8346
DOI - 10.17650/1818-8346-2019-14-2-8-12
Subject(s) - immunoglobulin light chain , paraproteinemias , monoclonal , hypoalbuminemia , medicine , hemodialysis , hypergammaglobulinemia , antibody , chemistry , monoclonal antibody , immunology
The objective of study is to estimate the efficiency of extracorporeal free light chains of immunoglobulin elimination in patients with monoclonal gammopathies (n = 12) during hemodialysis using selective filters. Materials and methods . A blood and dialysate free light chains concentrations change was criterion of efficiency. Results and conclusion . The selective free light chains filtration give the possibility of an adequate anti-tumor therapy, could prevent the development of irreversible renal failure and hypoalbuminemia.