Open AccessDOPAMINERGIC SYSTEM: STRESS, DEPRESSION AND CANCER (PART 2)
Author(s) -
О. А. Бочарова,
Е. В. Бочаров,
В. Г. Кучеряну,
Р. В. Карпова,
А. А. Вершинская
Publication year - 2019
Publication title -
rossijskij bioterapevtičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 1726-9792
pISSN - 1726-9784
DOI - 10.17650/1726-9784-2019-18-4-25-33
Subject(s) - dopaminergic , disease , immune system , depression (economics) , cancer , dopamine , metastasis , neuroscience , medicine , stress (linguistics) , chronic stress , fight or flight response , immunology , biology , linguistics , philosophy , economics , macroeconomics , biochemistry , gene
In today’s world, we are constantly exposed to stress. At the same time, if acute stress can have a positive effect on the body, constant stress usually harms health, leading to serious diseases, including cancer, which is considered to be age-related disease. It is also known that stress can significantly deteriorate the efficacy of chemotherapies and anti-tumour immune response, promote tumor growth and metastasis spreading. Meanwhile dopamin known to be antiaging and antistress agent is able to inhibit tumourgenesis. Therefore the role of Central neuronal processes involving the dopaminergic system in the mechanisms of malignant growth control is discussed in the present review.