Open AccessTHE COMBINED METHOD OF EFFECT PHOTODYNAMIC THERAPY AND RADIAL THERAPY ON SARCOMA М-1 OF RATS
Author(s) -
М. А. Каплан,
А. И. Малыгина,
Г. В. Пономарев,
Alesya Mikhailovskaya,
В. В. Дрожжина,
Л. М. Архипова,
J. S. Osipchuk
Publication year - 2015
Publication title -
rossijskij bioterapevtičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 1726-9792
pISSN - 1726-9784
DOI - 10.17650/1726-9784-2015-14-4-79-85
Subject(s) - photodynamic therapy , radiation therapy , medicine , sarcoma , combination therapy , laser therapy , nuclear medicine , surgery , pathology , chemistry , laser , optics , physics , organic chemistry
Antitumoral therapy of sarcoma M-l of rats is spent with use of the combined method of treatment (photodynamic therapy and radial therapy) at various sequences of its carrying out, at different time intervals and parametres of a laser irradiation. A photosensitinogen dose amidoaminchlorine and a gamma radiation dose were identical at all spent researches. The purpose: to study influence of all components of combined therapy and to define optimum conditions of its carrying out for achievement of significant antitumoral effect in comparison with monotherapy of each of them. As a result of researches intensifying of inhibiting effect is taped at complex therapy and optimum parametres of its carrying out are found.