Open AccessNosocomial infectious complications in patients with urological malignancies
Author(s) -
Н. В. Дмитриева,
В. В. Агинова,
И. Н. Петухова,
Е. Н. Соколова,
С. А. Дьякова,
З. В. Григорьевская,
Е. В. Кулага
Publication year - 2021
Publication title -
onkourologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 4
eISSN - 1996-1812
pISSN - 1726-9776
DOI - 10.17650/1726-9776-2021-17-1-126-133
Subject(s) - teicoplanin , acinetobacter baumannii , medicine , tigecycline , microbiology and biotechnology , enterococcus , linezolid , enterococcus faecium , daptomycin , klebsiella pneumoniae , pseudomonas aeruginosa , antimicrobial , staphylococcus aureus , acinetobacter , klebsiella , vancomycin , antibiotics , bacteria , escherichia coli , biology , biochemistry , gene , genetics
The objective of the study was to analyze the taxonomic structure of urinary infection pathogens and determine the susceptibility of ESKAPE group microorganisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterococcus spp.) isolated from cancer patients with nosocomial infections in 2018—2020 to antimicrobials. Materials and methods . 413 (71.9 %) strains of ESKAPE group bacteria from 228 patients were studied. Microorganisms were identified and antibiotic resistance was determined using Vitek-2 System (France) and MicroScan WalkAway (Germany / USA) analyzers. Results and conclusion . All gram-positive microorganisms were highly sensitive to vancomycin and teicoplanin, linezolid, tigecycline, and daptomycin, which can be used in the treatment if clinical indications are seen. Among gram-negative bacteria, the percentage of ESBL producers was 60—70 %, the percentage of carbapenem-resistant bacteria was minimalfor E. coli, rnmpared to the rest - 40—50 %, demonstrating the need to limit the use of carbapenems in the clinic.