Open AccessExpression of platelet-derived growth factor alpha and beta genes PDGFRA and PDGFRB associated with biochemical recurrence of prostate cancer after radical prostatectomy
Author(s) -
М. Ю. Шкурников,
Б. Я. Алексеев
Publication year - 2018
Publication title -
onkourologiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
H-Index - 4
eISSN - 1996-1812
pISSN - 1726-9776
DOI - 10.17650/1726-9776-2017-13-4-45-50
Subject(s) - pdgfrb , pdgfra , medicine , prostate cancer , prostatectomy , biochemical recurrence , cancer research , oncology , cancer , gene , biology , biochemistry , gist , stromal cell
We performed genome-wide transcriptome meta-analysis of prostate cancer samples after radical prostatectomy of patients without lymph node metastasis. Significant associations were determined between expression of platelet-derived growth factor alpha and beta genes (PDGFRA and PDGFRB) and probability and time of onset of biochemical recurrence.