Open AccessNeurofibromatosis 2: new perspectives in treatment (case report)
Author(s) -
Elizaveta Makashova,
S V Zolotova,
V. V. Kostyuchenko,
Mikhail Galkin,
М. А. Гинзберг,
Gleb Danilov,
Н. А. Антипина,
Н. А. Коновалов,
А. В. Голанов
Publication year - 2021
Publication title -
nejrohirurgiâ
Language(s) - English
Resource type - Journals
eISSN - 2587-7569
pISSN - 1683-3295
DOI - 10.17650/1683-3295-2021-23-1-109-118
Subject(s) - neurofibromatosis , medicine , radiosurgery , disease , radiation therapy , pharmacotherapy , bevacizumab , rehabilitation , pediatrics , surgery , radiology , physical therapy , pathology , chemotherapy
Neurofibromatosis 2 is one of the most prevalence disease among phakomatoses characterized by appearance of new central and peripheral nerve system tumors. The main treatment for this patient is a surgery, but in real time we observe the significant changes in treatment and rehabilitation in this patients including radiation therapy and pharmacotherapy. In this paper, we present the case of a different treatment options in young female with neurofibromatosis. She completed surgical treatment, Gamma Knife radiosurgery and bevacizumab on different stage of disease. Development of genetic and molecular methods and appearance of new way for treatment could help to achieve a good functional result and stable local control but new clinical and fundamental research are needed.