Open AccessPrevalence of human papillomavirus genotypes in women treated by the Unified Health System in a population from Northeast Brazil
Author(s) -
Karol Fireman de Farias,
Edilson Leite de Moura,
Adriely Ferreira da Silva,
Ithallo Sathio Bessoni Tanabe,
Eloiza Lopes de Lira Tanabe,
Denise Macêdo da Silva,
Ana Caroline Melo dos Santos,
Cristiane Araújo Nascimento,
Tiago Gomes de Andrade,
Danyelly Bruneska Gondim Martins,
Elaine Virgínia Martins de Souza Figueiredo,
J. L. Lima Filho
Publication year - 2020
Publication title -
diversitas journal
Language(s) - English
Resource type - Journals
ISSN - 2525-5215
DOI - 10.17648/diversitas-journal-v5i4-963
Subject(s) - genotype , human papillomavirus , sanger sequencing , population , nested polymerase chain reaction , polymerase chain reaction , virology , medicine , hpv infection , demography , hpv vaccines , gynecology , cervical cancer , biology , environmental health , cancer , dna sequencing , genetics , dna , gene , sociology
The aim of this study was to present the circulating HPV genotypes in a population from northeast Brazil. HPV was detected by nested-Polymerase Chain Reaction (nPCR) method using primers MY09/11 and GP5+/6+. HPV sequencing was performed by the method of Sanger. The HPV 16 was the most frequent (35.7%), followed by HPV 58 (14.3%). In conclusion, we identified, in one population from Northeast Brazil, a low prevalence of HPV 18 present in the vaccine provided by Unified Health System and a high prevalence of HPV 58 which is not present in this vaccine.
KEYWORDS: HPV, Oncology and Woman Healthy.