Open AccessTargeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation
Author(s) -
Koji Itahana,
Hua Mao,
Aiwen Jin,
Yoko Itahana,
Hilary V. Clegg,
Mikael S. Lindström,
Krishna Bhat,
Virginia Godfrey,
Gérard I. Evan,
Yanping Zhang
Publication year - 2007
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/zpfb-4472
Subject(s) - ubiquitin ligase , ubiquitin , mdm2 , ubiquitin protein ligases , ring finger , dna ligase , microbiology and biotechnology , chemistry , computational biology , biology , genetics , dna , biochemistry , gene