Open AccessInsulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim
Author(s) -
Sudharsan PeriyasamyThandavan,
Suchreet Takhar,
Adam J. Singer,
Michael R. Dohn,
William H. Jackson,
April Welborn,
Derek LeRoith,
Mario B. Marrero,
Muthusamy Thangaraju,
Shuang Huang,
Patricia V. Schoenlein
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/ywds-6g70
Subject(s) - antiestrogen , apoptosis , insulin like growth factor , cancer research , chemistry , growth factor , breast cancer , medicine , endocrinology , cancer , microbiology and biotechnology , biology , tamoxifen , receptor , biochemistry