Open AccessAirway Surface Dehydration by Transforming Growth Factor β (TGF-β) in Cystic Fibrosis Is Due to Decreased Function of a Voltage-dependent Potassium Channel and Can Be Rescued by the Drug Pirfenidone
Author(s) -
Dahís Manzanares,
Stefanie Krick,
Nathalie Baumlin,
John S. Dennis,
Jean Tyrrell,
Robert Tarran,
Matthias Salathé
Publication year - 2015
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/y465-sb03
Subject(s) - pirfenidone , transforming growth factor , cystic fibrosis , medicine , potassium channel , airway , ivacaftor , growth factor , pharmacology , anesthesia , cystic fibrosis transmembrane conductance regulator , lung , idiopathic pulmonary fibrosis , receptor