Open AccessAn orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Author(s) -
Timothy P. Sheahan,
Amy C. Sims,
Shuntai Zhou,
Rachel L. Graham,
Andrea J. Pruijssers,
Marco Agostini,
Sarah R. Leist,
Alexandra Schäfer,
Kenneth H. Din,
Laura J. Stevens,
James D. Chappell,
Xin Lü,
Tia M. Hughes,
Amelia S. George,
Colin Hill,
Stephanie A. Montgomery,
Ariane J. Brown,
Gregory R. Bluemling,
Michael G. Natchus,
Manohar Saindane,
Alexander A. Kolykhalov,
George R. Painter,
Jennifer L. Harcourt,
Azaibi Tamin,
Natalie J. Thornburg,
Ronald Swanstrom,
Mark R. Denison,
Ralph S. Baric
Publication year - 2020
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/xw2w-rr45
Subject(s) - virology , covid-19 , airway , microbiology and biotechnology , biology , coronavirus , cell culture , virus , broad spectrum , medicine , chemistry , pathology , genetics , outbreak , surgery , disease , infectious disease (medical specialty) , combinatorial chemistry