Open AccessConstruction of a hybrid β-hexosaminidase subunit capable of forming stable homodimers that hydrolyze GM2 ganglioside in vivo
Author(s) -
Michael B Tropak,
Sayuri Yonekawa,
Subha KarumuthilMelethil,
Patrick W Thompson,
Warren W. Wakarchuk,
Steven J. Gray,
Jagdeep S. Walia,
Brian L. Mark,
Don J. Mahuran
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/xbzh-1d23
Subject(s) - in vivo , protein subunit , ganglioside , hexosaminidase , hydrolysis , chemistry , biochemistry , biology , enzyme , genetics , gene