Open AccessNovel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease
Author(s) -
Subha KarumuthilMelethil,
Sahagabhushan Kalburgi,
Patrick Thompson,
Michael B. Tropak,
Michael D. Kaytor,
John G. Keimel,
Brian L. Mark,
Don J. Mahuran,
Jagdeep S. Walia,
Steven J. Gray
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/w4f0-sr84
Subject(s) - adeno associated virus , tay sachs disease , hexosaminidase , vector (molecular biology) , virology , genetic enhancement , disease , virus , biology , medicine , genetics , gene , pathology , biochemistry , recombinant dna , enzyme
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