Open AccessInhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome
Author(s) -
B. C. Capell,
M. R. Erdos,
J. P. Madigan,
James J. Fiordalisi,
R. Varga,
K. N. Conneely,
L. B. Gordon,
C. J. Der,
A. D. Cox,
F. S. Collins
Publication year - 2005
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/vfds-0231
Subject(s) - progeria , prenylation , lamin , chemistry , cancer research , medicine , biochemistry , enzyme , gene