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Effects on NaeI-DNA recognition of the leucine to lysine substitution that transforms restriction endonuclease NaeI to a topoisomerase: a model for restriction endonuclease evolution
Author(s) -
Kiwon Jo,
Michael D. Topal
Publication year - 1996
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/v8sv-2q32
Subject(s) - restriction enzyme , substitution (logic) , dna , endonuclease , topoisomerase , genetics , leucine , biology , microbiology and biotechnology , computer science , amino acid , programming language

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