Open AccessThe novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells
Author(s) -
Shih Ming Huang,
Jai Sing Yang,
Shih Chang Tsai,
Ming Hua Chen,
Meichun Hsu,
HuiYi Lin,
Li Chen Chou,
Jo Hua Chinag,
Kuo Hsiung̀ Lee,
Li Jiau Huang,
Sheng Chu Kuo
Publication year - 2011
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/tr7b-dh29
Subject(s) - chemistry , cyclin dependent kinase 1 , apoptosis , stereochemistry , microbiology and biotechnology , biology , cell cycle , biochemistry