Open AccessInterindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients: UGT2B7 *1c Is Associated With Faster Zidovudine Clearance and Glucuronidation
Author(s) -
Awewura Kwara,
Margaret Lartey,
Isaac Boamah,
Naser L. Rezk,
Joseph OliverCommey,
Ernest Kenu,
Angela D. M. Kashuba,
Michael H. Court
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/tkc8-jt77
Subject(s) - zidovudine , ugt2b7 , glucuronidation , pharmacokinetics , virology , reverse transcriptase , human immunodeficiency virus (hiv) , reverse transcriptase inhibitor , lamivudine , nucleoside , nucleoside reverse transcriptase inhibitor , medicine , pharmacology , chemistry , antiretroviral therapy , virus , enzyme , viral load , viral disease , stereochemistry , microsome , biochemistry , rna , hepatitis b virus , gene