Open AccessWhole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol
Author(s) -
Leslie A. Lange,
Youna Hu,
He Zhang,
Chenyi Xue,
Ellen M. Schmidt,
Zheng-Zheng Tang,
Chris Bizon,
Ethan M. Lange,
Joshua D. Smith,
Emily H. Turner,
Goo Jun,
Hyun Min Kang,
Gina M. Peloso,
Paul L. Auer,
Kuo-ping Li,
Jason Flannick,
Ji Zhang,
Christian Fuchsberger,
Kyle J. Gaulton,
Cecilia M. Lindgren,
Adam E. Locke,
Alisa K. Manning,
Xueling Sim,
Manuel A. Rivas,
Oddgeir L. Holmen,
Omri Gottesman,
Yingchang Lu,
Douglas M. Ruderfer,
Eli A. Stahl,
Qing Duan,
Yun Li,
Peter Durda
Publication year - 2014
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/shbq-nv48
Subject(s) - exome sequencing , pcsk9 , exome , computational biology , coding (social sciences) , cholesterol , ldl cholesterol , biology , genetics , mutation , ldl receptor , gene , lipoprotein , endocrinology , statistics , mathematics