
Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors
Author(s) -
Jeffrey L. Woodhead,
William J. Brock,
Sharin E. Roth,
Susan E. Shoaf,
Kim L.R. Brouwer,
Rachel J. Church,
Tom N. Grammatopoulos,
Linsey Stiles,
Scott Q. Siler,
Brett Howell,
Merrie Mosedale,
Paul B. Watkins,
Lisl K. M. Shoda
Publication year - 2017
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/s3rs-0s81
Subject(s) - tolvaptan , liver injury , drug , pharmacology , medicine , computational biology , intensive care medicine , biology , vasopressin