Open AccessIdentification of temperature-sensitive mutants of the human immunodeficiency virus type 1 protease through saturation mutagenesis : amino acid side chain requirements for temperature sensitivity
Author(s) -
Marianne Manchester,
Lorraine Everitt,
Daniel D. Loeb,
Clyde A. Hutchison,
R Swanstrom
Publication year - 1994
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/s31p-f288
Subject(s) - saturated mutagenesis , protease , mutant , mutagenesis , side chain , chemistry , saturation (graph theory) , biology , virology , biochemistry , enzyme , gene , organic chemistry , mathematics , combinatorics , polymer