Open AccessARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways
Author(s) -
Yanping Zhang,
Yujie Xiong,
Wendell G. Yarbrough
Publication year - 1998
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/rwgt-6m22
Subject(s) - mdm2 , cancer research , locus (genetics) , degradation (telecommunications) , microbiology and biotechnology , genetics , chemistry , biology , apoptosis , gene , computer science , telecommunications