Open AccessCharge-to-Alanine Mutagenesis of the Adeno-Associated Virus Type 2 Rep78/68 Proteins Yields Temperature-Sensitive and Magnesium-Dependent Variants
Author(s) -
Denise Gavin,
Samuel Young,
Weidong Xiao,
Brenda Temple,
C. R. Abernathy,
Daniel J. Pereira,
Nicholas Muzyczka,
R. Jude Samulski
Publication year - 1999
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/q35d-hq40
Subject(s) - alanine , mutagenesis , magnesium , chemistry , adeno associated virus , biochemistry , amino acid , mutation , gene , recombinant dna , organic chemistry , vector (molecular biology)