
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
Author(s) -
Jeff Staudinger,
B. Goodwin,
S. A. Jones,
D. Hawkins-Brown,
K. I. MacKenzie,
A. LaTour,
Y. Liu,
C. D. Klaassen,
K. K. Brown,
J. Reinhard,
T. M. Willson,
B. H. Koller,
S. A. Kliewer
Publication year - 2001
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/n3ej-at76
Subject(s) - pregnane x receptor , lithocholic acid , liver toxicity , nuclear receptor , toxicity , chemistry , environmental chemistry , liver x receptor , bile acid , pharmacology , biochemistry , biology , organic chemistry , transcription factor , gene