Open AccessIdentification of overlapping but distinct cAMP and cGMP interaction sites with cyclic nucleotide phosphodiesterase 3A by site-directed mutagenesis and molecular modeling based on crystalline PDE4B
Author(s) -
Wei Zhang,
Hengming Ke,
Anna P. Tretiakova,
Bradford A. Jameson,
Robert W. Colman
Publication year - 2001
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/n0ng-9p67
Subject(s) - mutagenesis , phosphodiesterase , identification (biology) , cyclic nucleotide phosphodiesterase , site directed mutagenesis , nucleotide , chemistry , cyclic nucleotide , cyclic gmp , computational biology , biochemistry , stereochemistry , biology , mutation , enzyme , gene , botany , mutant