
Synthesis and Preliminary Studies of a Novel Negative Allosteric Modulator, 7-((2,5-Dioxopyrrolidin-1-yl)methyl)-4-(2-fluoro-4-[ 11 C]methoxyphenyl) quinoline-2-carboxamide, for Imaging of Metabotropic Glutamate Receptor 2
Author(s) -
Akiko Hatori,
MingRong Zhang,
Lu Wang,
Rongjun Cheng,
Douglas J. Sheffler,
Tomoteru Yamasaki,
Lei Ma,
Yiding Zhang,
Xiaofei Zhang,
Nicholas D. P. Cosford,
Lihua Xie,
Katsushi Kumata,
Hye Jin Kang,
Steven H. Liang
Publication year - 2017
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/k9xc-4g16
Subject(s) - metabotropic glutamate receptor , allosteric modulator , quinoline , allosteric regulation , carboxamide , neuroscience , glutamate receptor , chemistry , metabotropic glutamate receptor 5 , metabotropic receptor , pharmacology , stereochemistry , psychology , biology , biochemistry , receptor , organic chemistry