Open AccessGDNF-expressing macrophages restore motor functions at a severe late-stage, and produce long-term neuroprotective effects at an early-stage of Parkinson's disease in transgenic Parkin Q311X(A) mice
Author(s) -
Y. Zhao,
Matthew J. Haney,
Y.S. Jin,
O. Uvarov,
N. Vinod,
Y.Z. Lee,
B. Langworthy,
J.P. Fine,
M. Rodriguez,
N. El-Hage,
Alexander V. Kabanov,
E.V. Batrakova
Publication year - 2019
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/k55v-3289
Subject(s) - parkin , neuroprotection , glial cell line derived neurotrophic factor , parkinson's disease , stage (stratigraphy) , genetically modified mouse , transgene , neuroscience , disease , biology , medicine , neurotrophic factors , genetics , gene , receptor , paleontology