Open AccessHuman amylin proteotoxicity impairs protein biosynthesis, and alters major cellular signaling pathways in the heart, brain and liver of humanized diabetic rat model in vivo
Author(s) -
Amro Ilaiwy,
Miao Liu,
Traci L. Parry,
James R. Bain,
Christopher B. Newgard,
Jonathan C. Schisler,
Michael J. Muehlbauer,
Florin Despa,
Monte S. Willis
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/k34z-j802
Subject(s) - amylin , proteotoxicity , in vivo , microbiology and biotechnology , signal transduction , neuroscience , biology , diabetes mellitus , chemistry , endocrinology , protein aggregation , genetics , islet