Open AccessA high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity: An antidote-controllable prothrombin RNA aptamer
Author(s) -
K. M. BOMPIANI,
D. M. MONROE,
F. C. CHURCH,
B. A. SULLENGER
Publication year - 2012
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/jbax-7x38
Subject(s) - antidote , aptamer , thrombin , thrombin generation , chemistry , rna , pharmacology , biochemistry , biophysics , medicine , biology , microbiology and biotechnology , platelet , organic chemistry , gene , toxicity