Open AccessGain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling
Author(s) -
Mahmoud Shobair,
Onur Dağliyan,
Pradeep Kota,
Yan L. Dang,
Haibo He,
M. Jackson Stutts,
Nikolay V. Dokholyan
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/hdex-ks42
Subject(s) - sodium channel , allosteric regulation , coupling (piping) , function (biology) , mutation , gain of function , chemistry , microbiology and biotechnology , biophysics , sodium , biology , biochemistry , materials science , enzyme , gene , organic chemistry , metallurgy