Open AccessAn adaptive design for identifying the dose with the best efficacy/tolerability profile with application to a crossover dose-finding study
Author(s) -
Anastasia Ivanova,
Ken Liu,
Ellen Snyder,
Duane Snavely
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/ff7w-jw59
Subject(s) - tolerability , crossover , crossover study , adaptive design , medicine , computer science , medical physics , pharmacology , artificial intelligence , clinical trial , alternative medicine , adverse effect , pathology , placebo