Open AccessNelfinavir-Resistant, Amprenavir-Hypersusceptible Strains of Human Immunodeficiency Virus Type 1 Carrying an N88S Mutation in Protease Have Reduced Infectivity, Reduced Replication Capacity, and Reduced Fitness and Process the Gag Polyprotein Precursor Aberrantly
Author(s) -
W. Resch,
R. Ziermann,
N. Parkin,
A. Gamarnik,
R. Swanstrom
Publication year - 2002
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/ev3s-6955
Subject(s) - nelfinavir , amprenavir , virology , protease , mutation , infectivity , biology , virus , enzyme , genetics , biochemistry , gene , antiretroviral therapy , hiv 1 protease , viral load