Open AccessUse of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations
Author(s) -
M.H. Kowalski,
H. Qian,
Z. Hou,
J.D. Rosen,
A.L. Tapia,
Y. Shan,
D. Jain,
M. Argos,
D.K. Arnett,
Christy L. Avery,
K.C. Barnes,
L.C. Becker,
S.A. Bien,
J.C. Bis,
J. Blangero,
E. Boerwinkle,
D.W. Bowden,
S. Buyske,
J. Cai,
M.H. Cho,
S.H. Choi,
H. Choquet,
L. A. Cupples,
M. Cushman,
M. Daya,
P.S. de Vries,
P.T. Ellinor,
N. Faraday,
M. Fornage,
S. Gabriel,
Sruthi Ganesh,
M. Graff,
N. Gupta,
J. He,
S.R. Heckbert,
B. Hidalgo,
Chani J. Hodonsky,
M.R. Irvin,
A.D. Johnson,
E. Jorgenson,
R. Kaplan,
S.L.R. Kardia,
T.N. Kelly,
C. Kooperberg,
J.A. Lasky-Su,
R.J.F. Loos,
S.A. Lubitz,
R.A. Mathias,
C.P. McHugh,
C. Montgomery,
J.-Y. Moon,
A.C. Morrison,
N.D. Palmer,
N. Pankratz,
G.J. Papanicolaou,
J.M. Peralta,
P.A. Peyser,
S.S. Rich,
J.I. Rotter,
E.K. Silverman,
J.A. Smith,
N.L. Smith,
K.D. Taylor,
T.A. Thornton,
H.K. Tiwari,
R.P. Tracy,
T. Wang,
S.T. Weiss,
L.-C. Weng,
K.L. Wiggins,
J.G. Wilson,
L.R. Yanek,
S. Zöllner,
K.E. North,
P.L. Auer,
NHLBI Trans-Omics for Precision Medicine Consortium,
TOPMed Hematology Hemostasis Working Group,
Laura M. Raffield,
A.P. Reiner,
Y. Li
Publication year - 2019
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/e6ew-j192
Subject(s) - imputation (statistics) , genome wide association study , african american , precision medicine , computational biology , genetics , medicine , biology , single nucleotide polymorphism , gene , computer science , genotype , missing data , machine learning , history , ethnology