Open AccessHigh Affinity for Farnesyltransferase and Alternative Prenylation Contribute Individually to K-Ras4B Resistance to Farnesyltransferase Inhibitors
Author(s) -
James J. Fiordalisi,
Ronald L. Johnson,
Carolyn Weinbaum,
Kaoru Sakabe,
Zhui Chen,
Patrick J. Casey,
Adrienne D. Cox
Publication year - 2003
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/akhj-ca31
Subject(s) - farnesyltransferase , prenylation , farnesyltransferase inhibitor , chemistry , biochemistry , enzyme