Open AccessPyrimidine Ribonucleotides with Enhanced Selectivity as P2Y 6 Receptor Agonists: Novel 4-Alkyloxyimino, (S)-Methanocarba, and 5′-Triphosphate γ-Ester Modifications †
Author(s) -
Hiroshi Mitani,
Matthew O. Barrett,
Hyojin Ko,
Dilip K. Tosh,
Artem Melman,
Lauren E. Burianek,
R. Balasubramanian,
Barkın Berk,
Stefano Costanzi,
T. Kendall Harden,
Kenneth A. Jacobson
Publication year - 2010
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/9vwt-ya70
Subject(s) - selectivity , chemistry , pyrimidine , receptor , nucleotide , p2y receptor , agonist , biophysics , biochemistry , biology , gene , catalysis