Open AccessAn Allosteric Modulator of 7 Nicotinic Receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), Causes Conformational Changes in the Extracellular Ligand Binding Domain Similar to Those Caused by Acetylcholine
Author(s) -
S. C. Barron,
James T. McLaughlin,
J. A. See,
V. L. Richards,
Robert L. Rosenberg
Publication year - 2009
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/8p87-n233
Subject(s) - allosteric regulation , chemistry , urea , nicotinic agonist , stereochemistry , ligand (biochemistry) , extracellular , allosteric modulator , receptor , conformational change , biophysics , biochemistry , biology