Open AccessThe primary glucose-lowering effect of metformin resides in the gut, not the circulation: Results from short-term pharmacokinetic and 12-week dose-ranging studies
Author(s) -
J.B. Buse,
R.A. DeFronzo,
J. Rosenstock,
T. Kim,
C. Burns,
S. Skare,
A. Baron,
M. Fineman
Publication year - 2016
Publication title -
carolina digital repository (university of north carolina at chapel hill)
Language(s) - English
DOI - 10.17615/72md-s752
Subject(s) - metformin , pharmacokinetics , circulation (fluid dynamics) , term (time) , systemic circulation , medicine , pharmacology , chemistry , endocrinology , insulin , physics , quantum mechanics , thermodynamics